Intervention with Hybrid Imaging

Author: Nilima Das

Pelvic cancer pain is rarely simple—and advanced disease almost never respects textbook anatomy.
For pain physicians managing patients with advanced pelvic malignancies, achieving effective analgesia while maintaining safety can be profoundly challenging. Conventional imaging techniques, when used in isolation, may fail to reveal critical anatomical distortions—sometimes with serious consequences.

This case-based discussion highlights why hybrid ultrasound–fluoroscopy guidance can redefine safety and success in superior hypogastric plexus neurolysis (SHPN), especially in patients with altered pelvic anatomy Document.


The Clinical Reality of Pelvic Cancer Pain

Pelvic malignancies often produce deep, visceral, poorly localized pain that progressively worsens with disease advancement. While opioids remain the cornerstone of cancer pain management, they frequently come at a cost:

  • Sedation and cognitive impairment
  • Constipation and bowel dysfunction
  • Reduced quality of life and loss of independence

Interventional procedures such as superior hypogastric plexus neurolysis offer opioid-sparing, long-lasting pain relief. However, their success depends heavily on accurate needle placement and anatomical clarity.


Why “Textbook Anatomy” Fails in Advanced Pelvic Cancer

In advanced disease, pelvic anatomy is often profoundly distorted:

  • Tumor mass extends beyond the expected anatomical planes
  • Ureters become dilated, tortuous, and displaced
  • Major vessels (IVC, iliac vessels) shift from normal positions
  • Metastatic deposits obscure conventional needle trajectories

Fluoroscopy, while excellent for bony landmarks, cannot visualize soft tissues. As a result, structures such as ureters and bowel loops may remain invisible—until they are injured.

In this case, a previous fluoroscopy-guided SHPN attempt was abandoned due to accidental ureteric puncture, despite apparently acceptable fluoroscopic views.


Seeing More: Why Hybrid Imaging Matters

Rather than choosing between imaging modalities, the approach was reframed:

Why not use both ultrasound and fluoroscopy together?

What Ultrasound Added

  • Real-time visualization of soft tissues
  • Identification of a dilated and displaced ureter
  • Recognition of bowel loops and metastatic masses
  • Continuous needle–organ relationship monitoring

What Fluoroscopy Confirmed

  • Correct vertebral level and depth
  • Safe contrast spread pattern before neurolysis
  • Classical radiographic confirmation of plexus access

This complementary imaging strategy transformed a high-risk procedure into a controlled, step-wise intervention.


Clinical Outcome: Small Adjustment, Major Impact

The results were clinically meaningful:

  • >70% reduction in pain scores within 24 hours
  • 75% reduction in opioid requirement
  • Improved sleep and daily functioning
  • No procedural complications

Most importantly, the patient experienced meaningful relief after months of refractory pain and a failed prior intervention.


Why This Case Matters Beyond One Patient

This experience carries broader implications for pain physicians and palliative care teams:

  • Distorted anatomy should not automatically exclude interventional options
  • Multimodal imaging significantly improves procedural safety
  • Ultrasound enhances anatomical awareness
  • Fluoroscopy provides procedural assurance
  • Together, they expand the boundaries of what is safely achievable

A Shift in Interventional Pain Thinking

This is not merely a technical success—it reflects a change in mindset.

Better outcomes do not always require new drugs or expensive technology. Sometimes, they come from using existing tools more intelligently.

When anatomy no longer follows the rules, our approach must evolve accordingly.


Take-Home Message for Pain Physicians

Hybrid ultrasound–fluoroscopy guided superior hypogastric plexus neurolysis is a safe, effective, and practical solution for pelvic cancer pain in patients with distorted anatomy—particularly when conventional fluoroscopy-only techniques fail.

In complex pain management, seeing more truly means hurting less.

Authored by: Dr Nilima Das

Reviewed and edited by: Dr Gautam Das

Read a case report by Dr Nilima Das: https://journals.lww.com/jmupm/fulltext/2025/01000/a_multimodal_imaging_technique_for_superior.7.aspx

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